Try to get rid of all your cards before the computer does. Drag one card at a time from your hand (bottom) to one of the four discard piles in the middle of the screen. If the arow under the deck is point up, place a cards that is 1 rank higher on top. If the arrow is pointing down, place a card 1 lower in rank. Going up after 13 is 1 and going down from 1 is 13.
There are 3 special cards:

Wild cards can be placed on any card and any card can be placed on top of them
Red cards with a circular arrow on them wil reverse the direction of the deck
Lighning cards will score a bonus if you place then on top of other lightning cards.